This study examined the entrepreneurial skill needs of Economics education graduates for effective management of small-scale businesses in South-Eastern Nigeria. The study adopted a descriptive survey research design. The sample for the study was 253 respondents, which comprised 120 Small scale business entrepreneurs and 133 Economics Education graduates from public universities in the South-East geopolitical zone of Nigeria, using a multi-stage sampling procedure. The instrument for data collection was a 29-item researcher developed questionnaire titled “Entrepreneurial Skill Needs for Effective Management of Small-Scale Business Questionnaire (ESNEMSBQ)”  Out of the 253 questionnaires distributed to respondents, 241, constituting 95%, were returned and included in the data analysis. The Weighted Mean and Improvement Need Index analysis were used to address the research questions while a t- test statistic was used to test the hypotheses at the 0.05 level of significance. The results showed that the graduates of Economics education need creative skills, computer literacy skills and accounting skills for effective management of small-scale businesses. The study recommends that Economics education lecturers should undergo regular training and workshops to acquire various entrepreneurial skills. These acquired skills can then be imparted to students, thereby enhancing their entrepreneurial capabilities.